North Castle Ventures

News and field notes

Announcements from the portfolio and observations on the convergence of physical real estate, sovereign infrastructure and enterprise AI.

Featured

Open Standard

August 8, 2026

3 min read

North Castle Ventures Publishes the AI-Native Medical Specification, Extending Sovereign Edge Compute to Clinical Real Estate

The vendor-neutral specification defines a zero-egress compute node built into the Medical Office Building, and is published under CC-BY-4.0 with a citable DOI alongside its AI-Native Office sibling.

Read story

Latest stories

5 stories

July 23, 2026Joint Venture

North Castle Ventures and Trucast.AI Form Native Agentic LLC to Deploy Sovereign Edge Compute

The joint venture operationalizes the AI-Native Office standard, deploying Nate within the physical footprint of the Armonk Professional Center.

July 16, 2026AI Infrastructure

Thinking Machines Lab Releases Inkling, a 975-Billion-Parameter Multimodal Model Built for Text, Audio and Vision

Inkling combines text, audio and vision in one native multimodal model, with open weights and deployable infrastructure aimed at serious production use.

July 16, 2026Open Standard

North Castle Ventures Principals Co-Author the AI-Native Office RFC, Establishing Global Physical Standards for Edge Compute

The RFC establishes an open standard for acoustic isolation, fiber networking and localized compute integration in Class A commercial real estate.

July 9, 2026Leasing

North Castle Ventures Launches 355 Main as a Destination Workplace; Announces Pre-Leasing Sellout

The adaptive reuse of 355 Main Street resulted in the complete pre-leasing of the second-level full-floor flagship suite.